Two preseason games cap Week 2 with Falcons-Titans at 7 p.m. ET and Chiefs-Seahawks at 10 p.m. ET. This slate emphasizes volatile backfields and high-variance pass-catching corps rather than pure cost efficiency, making Week 2 DFS a showcase for late-round and backup options. Key themes: Titans injuries push Mullings and Chestnut into work, Seattle mixes George Holani against KC-level competition while Kenneth Walker III handles heavy workload management, and slivers of upside exist at WR spots for Young, Drummond, and Royals in Seattle and KC’s DST pressure on Levis and Darnold. Expect a mix of floor-leaning plays and the occasional breakout score in a weekend that rewards aggressive exposure to secondary options.

QBs Milroe and Stick receive opportunity ceilings as backups with run-heavy appeal, while Panthers' Darnold and Seahawks' Lock provide contrast in style and matchup. Running backs Mullings and Chestnut in Tennessee, Walker in Seattle, and the Holani-Martinez dueling narrative in Seattle offer fantasy-friendly plots as rosters tighten. At receiver, deep looks for Young, Drummond, Royals, and Tonyan at Seattle provide GPP-grade upside in limited-action formats. In short, capitalize on volume and role clarity emerging from Week 1 while preserving salary flexibility for Week 3 considerations.

Tennessee Titans training camp injury roundup ahead of joint practices with the Atlanta Falcons centers on Quandre Diggs returning to team drills and Lloyd Cushenberry eyeing on-field work after his Achilles tear. Blake Hance and Cushenberry could join midweek if cleared, while Cushenberry must come off the PUP list before practicing. Titans will likely be without Tyjae Spears (ankle), T’Vondre Sweat (tonsillectomy) and Kevin Winston Jr. (knee soreness) this week, with Winston unlikely to rush ACL rehab. Anfernee Orji faces probable IR after an ACL injury in a previous joint session with Tampa Bay. The week shapes depth charts and plan as joint practices vs. Atlanta test the roster’s resilience.

As fantasy players, note Diggs’ health and Cushenberry’s return timeline, which could unlock the Titans’ interior protection and secondary coordination. Spears’ absence opens snaps for others in the backfield, while Orji’s looming IR status could push inside-linebacker depth to the forefront. The Falcons’ side of the cap will also be watched in joint sessions, as practice tempo and scheme could hint at early-season roles and matchup-specific shifts. The story is a snapshot of a team in flux, balancing rehab, return timelines and competition for immediate rotation spots.

Tyjae Spears exits early with an ankle injury in a 29-7 preseason loss to Tampa Bay, likely sidelining him for much of the rest of August. Nashville hints that Spears could miss a couple of weeks, leaving Week 1 timeline uncertain as the Titans search for a reliable backfield path. Brandon Allen connected with Spears on a third-and-long play before the injury, underscoring Spears’ role as a versatile piece in Brian Callahan’s offense when healthy.

The Titans’ depth chart behind Spears includes Julius Chestnut, Kalel Mullings, Jermar Jefferson, and Jordan Mims. Mullings led the group against the Bucs with seven carries for 33 yards and provided special-teams value alongside Chestnut. Tennessee faces two joint practices with Atlanta this week before their next preseason game, then opens the regular season at Denver, intensifying the fantasy ripple effects as Spears’ timetable remains murky.

Historically, Spears has battled ankle sprains, a hamstring issue, and concussions, complicating any quick return timeline. The absence could thrust Tony Pollard into a larger workload early, with Mullings and Chestnut absorbing more touches as the backup committee. For fantasy managers, the injury elevates the need to monitor practice reports, potential Week 1 readiness, and how the Titans restructure their early-down and passing-game usage in Spears’ absence.

Tennessee’s Tyjae Spears will miss the remainder of the preseason due to a high ankle sprain, with team officials hopeful he can return for Week 1 against Denver. Spears has battled injuries in recent seasons but flashed multi-tools as a rookie (453 rushing yards, 2 rushing TDs and 52 receptions for 385 yards; 536 total yards and 5 TDs last year). The injury opens up backfield opportunities in the short term as Tennessee leans on Pollard and a pair of backups to absorb carries as Spears heals.

In the near term, Pollard is positioned for a larger workload after a Pro Bowl-caliber season that saw 1,079 rushing yards. Kalel Mullings and Julius Chestnut figure to benefit if Spears’ absence extends, with Mullings’ 948 rushing yards and 12 TDs at Michigan and Chestnut’s 22-carry tally last season providing a path to increased touches. Fantasy managers should monitor Spears’ timeline and the Titans’ depth chart as Week 1 looms against Denver.